Its small seeds appear in several early egyptian, lybian and near eastern sites from about 4000 bc. The benefits, dosage and side effects of citrullus colocynthis. Phenolic compounds and antiradical properties of methanolic extracts of citrullus colocynthis and plantago major in iran afsaneh moslemi mehni 1, fatemeh shahdadi 2 1young researchers and elite club, jiroft branch, islamic azad university, jiroft, iran 2department of food engineering, jiroft university, iran key words. Citrullus colocynthis is a very droughttolerant medicinal species, closely related to watermelon c. Pdf topical citrullus colocynthis in painful diabetic. As already mentioned, that flour enriches and thickens soups as well as other foods. Homeopathy a homeopathic remedy used for colic, neuralgia caused by suppressed emotions, gastric pain, headaches accompanied by nausea and vomiting, gout, rheumatic complaints, and vertigo. Insulinomimetic effect of citrullus colocynthis roots in stz.
Solvent extraction of citrullus colocynthis fruit pulp was done by. Molecular data, including sequences from the original collection of momordica lanata made near cape town by c. Effects of hydroethanol extract of citrullus colocynthis. Nov 19, 2017 citrullus colocynthis has a number of interesting names like indrayan hindi, bitter apple, vine of sodom, and desert gourd. The plant has small, pale greenish yellow flowers, forked tendrils, and. Citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally. The main clinical feature was acute rectorrhagia preceeded by mucosal diarrhea with tenesmus, which gradually progressed to bloody diarrhea and overt rectorrhagia within 3 to 4 hours. Phenolic compounds and antiradical properties of methanolic. There have been reports of death following ingestion of just. An improved hplc method for determination of colocynthin in. Evaluation and characterisation of citrullus colocynthis l. The genus citrullus includes four species, all native to arid regions of africa and eurasia.
Bitter apple scientific name the scientific name for this plant is citrullus colocynthis. Effects of alkaloid rich extract of citrullus colocynthis fruits on artemia salina and human cancerous mcf7 and hepg2 cells aniruddha mukherjee, savita d patil abstract in the present research the anticancer effect of alkaloid rich extract of citrullus colocynthis fruits was investigated. Effect of citrullus colocynthis schrad fruits on testosteroneinduced alopecia. Roots of a small leptadenia pyrotechnica bush were observed to spread throughout 850 m3 of soil to a depth of 11. Effects of alkaloid rich extract of citrullus colocynthis. To evaluated the differential effects of ethanol extraction of citrullus colocynthis c. Issn phytochemical analysis of a folklore medicinal plant. Pdf tissue culture and plant regeneration of watermelon. Hepatorenal effect of single or combined moringa olivera. It is also used in combination products for treating liver and gallbladder ailments. The findings revealed that citrullus colocynthis possess a very strong antihyperglycemic potential justifying. Safety evaluation studies of citrullus colocynthis for. Cucurbitacins from the leaves of citrullus colocynthis l. Citrullus colocynthis cct fruit also known as bitter cucumber is native to dry areas of north africa, the mediterranean basin and asia.
Colocynth extracts prevent epithelial to mesenchymal transition. Chapter 5 discussion the common guava tree psidium guajava is popular in an indigenous system of folk. It was banned by the food and drug administration in 1991 taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. Meena and panti, 2008 have isolated and identified quercetin by tlc from citrullus colocynthis linn.
Colocynth definition of colocynth by the free dictionary. Phytochemical analysis of a folklore medicinal plant citrullus colocynthis l bitter apple c. Citrullus is a genus of seven species of desert vines, among which citrullus lanatus the watermelon is an important crop. Effects of hydroethanol extract of citrullus colocynthis on blood.
Effect of citrullus colocynthis on hair growth in albino rats. It is distributed among the west coast of northern africa, eastward through the sahara, until india 6. It was always known as a toxic gourd but was turned to as a food in desperate times. Mar 20, 2006 citrullus colocynthis is a desert plant with a rich history as an important medicinal plant and as a source of valuable oil. The colocynth grows in sandy, coastal, or desert soils and commonly spreads vegetatively. A qualitative analysis was performed for the identification of the presence. Files are available under licenses specified on their description page. Indeed, if you will imagine a watermelon vine bearing a small, hard fruit with a bitter pulp, you. Pdf the clinical investigation of citrullus colocynthis. Out of scope information includes radiopharmaceuticals, contrast media. Citrullus colocynthis cucurbitaceae is a perennial herb usually trailing. This is a dangerously powerful plant that has been found to work as a medicine in ayurveda as well as homeopathy.
Effect of citrullus colocynthis schrad fruits on testosterone. Known hazards the plant contains a number of potentially toxic compounds and can be harmful if used in quantity. The fruit pulp of colocynth has medicinal properties while the seeds have nutritive qualities. Citrullus colocynthis is a phreatophyte with low tolerance to salinity brown et al. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. Citrullus colocynthis fruits were also traditionally used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes 47. Bitter apple common names bitter apple trees are also known by a host of common. These plants have lemonsized fruits which are known for their medicinal properties. Citrullus colocynthis, cucurbitaceae, indravaruni, bitter apple. Insecticidal activity and biochemical composition of citrullus.
Colocynth, citrullus colocynthis, hairystemmed perennial vine of the gourd family cucurbitaceae, native to the mediterranean region. The aqueous and ethanolic extracts of citrullus colocynthis aecc and eecc at. Phylogeography of the bitter apple, citrullus colocynthis. Despite its promise for the food industry, it is the smallscale, subsistence use that most concerns us here. Citrullus colocynthis 2 growth its fruit, which is lemonsized, yellowish, greenmottled, spongy, and extremely bitter, is a powerful hepatic stimulant and hydragogue cathartic. Citrullus colocynthis is a medicinal plant that has anticancer property mediated by apoptosis. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while. Intensification of rangeland grazing in an oilrich state. The findings revealed that citrullus colocynthis possess a very strong anti hyperglycemic potential justifying. Taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. Citrullus colocynthis definition of citrullus colocynthis. New state records for citrullus, cucumis, and cucurbita cucurbitaceae outside of cultivation in the usa.
Citrullus colocynthis as the cause of acute rectorrhagia. Minoxidil 2% solution was applied topically and served as the standard. Schrad, which has been used in traditional and ethno medicine of many. Akobundu authors cherry and simmons are affiliated with the usda.
The family also includes pumpkin, squash, melon, and cucumber 3. The authors suggested that combining the use of reflective mulch and host. Despite serious safety concerns, colocynth is used for diabetes, high cholesterol and blood fats called triglycerides, constipation, and tuberculosis. To examine the safety and efficacy of citrullus colocynthis c. Egusi seed is botanically known as citrullus colocynthis curcurbita citrullus l. The knowledge on rivers is intensively studied in addition to the distribution of plant diversity, richness of species is also used for effective. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Starting dose calculation for medicinal plants in animal. In western australia it can be found it a wide variety of habitats including open woodlands, grasslands, river beds and banks. A watermelon can be 570cm long and weigh up to 30kg. All structured data from the file and property namespaces is available under the creative commons cc0 license.
Its botanical name is citrullus colocynthis and it belongs to cucurbitacae family. The study was designed as a twoarm, doubleblind randomized placebocontrolled. Sciatica therapy arnica montana citrullus colocynthis fruit pulp pseudognaphalium obtusifolium hypericum perforatum potassium iodide magnesium phosphate, dibasic trihydrate toxicodendron pubescens leaf tablet, orally disintegrating number of versions. Citrullus colocynthis cct, also known as bitter apple, wild gourd, tumba and wine of sodom, is known for its medicinal value since long. It is known by various names such as bitter cucumber, pumpkin seeds, egusi melon, vine of sodom plant, wild gourd, bitter apple, colocynth or desert gourd. Citrullus colocynthis on integrated taxonomic information system. Jun 14, 2018 citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. Colocynth citrullus colocynthis is an environmental weed in the northern territory, western australia and victoria.
Citrullus colocynthis fruits are usually recognized for its wide range of medicinal uses as well as pharmaceutical and nutraceutical potential. Other side effects include convulsions, paralysis, and death. This page was last edited on 23 december 2019, at 06. Toxic effect of citrullus colocynthis on liver ijpt. Hosted by the usgs core science analytics and synthesis. Sequence information deduced from several polymorphic intergenic cpdna regions and a relatively large intron 0. Citrullus colocynthis at encyclopedia of life citrullus colocynthis at national center for biotechnology information. Citrullus colocynthis is a very droughttolerant medicinal species, closely related to. Despite serious safety concerns, colocynth is used in combination products for treating constipation, liver, and. Pdf citrullus colocynthis cct is a medicinal herb known for its multiple.
Pdf the analysis of variation in morphological traits differentiated citrullus colocynthis populations growing north of qena. Leg and back pain relief capsicum annuum, colocynthis, gnaphalium polycephalum, magnesia phosphorica tablet out of scope out of scope for rxnorm and will not receive rxnorm normal forms. Schrad is a valuable cucurbit plant, widely distributed in the desert areas of the world. Citrullus colocynthis contained carbohydrate, protein, separated amino acid, tannins, saponins. Effect of citrullus colocynthis on hair growth in albino rats r. Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter cucumber, desert gourd, citation needed egusi, vine of sodom, or wild gourd, is a desert viny plant native to the mediterranean basin and asia, especially turkey especially in regions such as izmir, and nubia. These compounds include elatermidine, glycosides, resin, dihydric alcohol, heltiacontane, citrullin and citrullinic acid.
It was banned by the food and drug administration fda in 1991. Cucurbitaceae is a valuable plant widely distributed cucurbitaceae is a valuable plant widely distributed in the desert areas of the world including tunisia 6,7. Melitopolski article pdf available in plant cell reports 85. Colocynthis, bitter apple, bitter cucumber, colocynth. Schrad is a valuable plants from cucurbitaceae family, widely distributed in the barren region, is a nonhardy, herbaceous perennial vine, branched from the base 4. Orszagos kemiai biztonsagi intezet egeszsegugyi toxikologiai tajekoztato szolgalat ettsz mergezo anyagok altal okozott tunetek es elvaltozasok budapest 2011 aceton szagu lehelet halitosis a felsorolt. Characterization of watermelon citrullus lanatus var. The serums, tg, chol, ldlc, hdlc, sgot and sgpt were measured with enzymatic methods. Thunberg in 1773, show that what thunberg collected is not what has been called. Insecticidal activity and biochemical composition of citrullus colocynthis, cannabis indica and artemisia argyi extracts against cabbage aphid. Citrullus colocynthis supplement health benefits, dosage. Page designed through the cooperative efforts of interagency itis teams. Alopecia is a psychologically distressing phenomenon. The clinical investigation of citrullus colocynthis l.
Pdf genetic diversity of colocynth citrullus colocynthis schrader. Therapeutic effects of citrullus colocynthis fruit in. Four patients with colocynth intoxication are presented. Citrullus colocynthis plant has a strong laxative property and application of high dosages of this herbal drug can cause diarrhea, painful cramps, and bloody diarrhea in humans. Dailymed sciatica therapy arnica montana citrullus. The berries have many seeds, or none in the case of the triploid hybrid seedless watermelon 8,10,12. Chemical, functional, and nutritional properties of egusi.
Persons familiar with the common watermelon vine need no description of the plant which produces colocynth apples. Sekar abstract phytochemical screening of citrullus colocynthis belonging to the family cucurbitaceae was carried out for finding its medicinal values. Tissue culture and plant regeneration of watermelon citrullus vulgaris schrad. Colocynth citrullus colocynthis uses, dosage, side effects. Root density correlated with soil moisture content throughout the depth batanouny and wahab, 1973. Chemical constituents and pharmacological effects of.
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